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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01ec31f415020e9f9881d18f291218b16887d6a370ddbb8036c5025d51a1da84' 
  AND token = 'My8AtnmlILGdOjfGUr54YRHlayco1g9WGL4SJDQSMQU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}