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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b34bb51240f370eee4327593afcd64d9365eb1427a4a6cc66d30deb22716638' 
  AND token = '/LaZkafIrZ2YE4vyX162YxfpBui3Yv2P356JmQjJUys=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}