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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '78d61bcae83f55ea347d06ef4acf2eacc651f94ccc933b177feb86f4605d7aa6' 
  AND token = '1L/hDSoTBcjMnE7aGhg6i9HbwvUDsNJ3UnIexWQRcdc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}