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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2fe80fd3c3b32ce2f4439583472c69ea9a83503c521b616a281f38a1e922fd26' 
  AND token = '+6qtOES13kbNsOYLlvHNBKCeRrc98X1dCijMbuA8/00=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}