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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0a35c299a25c4f555fd1e6684866951f1ff3fbb25783cc3b4b35f33adec62406' 
  AND token = 'FyRfDykoebknJU18uI2jmz5LVNotvAkZDp+4Di8xlUk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}