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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '284ca2adcbcaed2519be9b919e95c6d2bf1d7d0170a65488d0a31a30786cedb0' 
  AND token = 'WAvwE8jY3V/UWmQrotekAKEIqgb07NsLNZDhWeGU8IU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}