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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '72ba9e8a09e8d7200b37afcc3fe7fb12ee42337a9f8bce2624c3eb3786e4f244' 
  AND token = '+lRogDNCdL7MDszfyCOylBLh/pdGAoXEU09+XURArPg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}