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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25883e0fe6c12eacfbcbdb31b00d779069c24bb047c4a76c668aed79b7147f5d' 
  AND token = 'HcNK8jycX8XNjE/KewuPu/NsG1XDY8J8FyEKe+BY2q8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}