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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2da6cf0477b3f80f45a0ddc16f0fbf51c825a357c0fef5c5f52a7298ef4ceaae' 
  AND token = 'cZBX5p0SOFyv5ESGvRPv49UlZFTV8FkcmCbzV9ecF1s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}