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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e76e450ea82e89cdfc1c857d691a1f5db53b60449dcb36980b5fb0336e5f6ca' 
  AND token = '0V9KU37/G3LuPYqdkkZuGygWpCvMXEc1Ez9vvuAc6Mw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}