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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d1e704f3d1c3f5818530f689656a6fd9cf34cdc7ff4fd1668cca05802d10887' 
  AND token = '6uQ2thXo1pimF+ui+MLhKm7CkVfKNyAZt9ujv4SnwXE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}