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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cfdc3c9fd029ff91f201e488443fe18acbc20b8cff78f3fddcf5e90c4e4db305' 
  AND token = 'J57Ud9KJfcFjQVLV2ts2ELS1CEuxyD9jnCqCDRN4NE0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}