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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '27501a1c12a6e52d044d33c2418a75127d82b3bfdc8684986e819450373328d2' 
  AND token = 'wiFzB7lTDLoFBiyo7AZnkRmGstAekjNeJ5VYnFQZY0w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}