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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ef16c3fab384162a7ba3994f16211dea628e506c2d3e777eab42d3d4fa1bc35' 
  AND token = 'he9dxMmLdppm9zFbragH7Kz3Ud4LJgBYmCbZ4ax+K7Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}