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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '981a224d035170e00262e178553060aa723a93f6e741d38ce963c262a313bbf4' 
  AND token = 'aVQPJDEvhoUnHZysT7NR9ntuG0NL2UXDvOkFmlz4D0g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}