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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '899c757fc59d6ad88461b7e3fa638ed75f2b2d7d1f8c27525f28b0b706122cb2' 
  AND token = 'ntbQ5tNH2cr1wqWWjdsrq7Gu7fPf+kuEf7LF50HWMa0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}