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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a0db80d530279c6665bfd41dd465a935ac2a853e9b3dabb8834567c48927ae9d' 
  AND token = 'TcuRKHC6LrgDJEPVo5IrgC49x15+MJhy/zr1QsBfNmc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}