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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ac63e87dda67532e0bf9f73eb78d579354cf7ee7e24a31b6d38543211cd0421' 
  AND token = 'YmcE4g1r1hx1ej59jWOVaMiSELFE9d7Lc7lVaXa9btw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}