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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8866379a020f81489762239697c29779bff1b569a91ce34d1f1f548f60970cee' 
  AND token = 'ShxFCLlUxvT2lBemhaBp3T8Sc6ZomsQdnLxT8n79CGE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}