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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea2346ab696be94ce14c89e6764048b325c371fabc807f19b44d3c245aa5fb2c' 
  AND token = '0iEHyuKtDGNEvjuA6ygR2fexQZE0gqHyJ+Ru8NXFHiY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}