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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '18bf6bb3a695c21b1138f97bb08ad21aba4556c4e9846fc6c6d757d526528a0f' 
  AND token = 'mq5J+0U91mcY2jHW9ytesJXSW2Njk3TuyivDlbRDFWg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}