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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41b6e64e7c099101107db674f176a21479a265e4033293762af1f19f9ecc057e' 
  AND token = 'iPDlp73Dgcs3fcywmFGB/QPVDhWwqrKQru5lPKCTX9w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}