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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa321e1f0d4b380937aadcbd40ab3d63db3696f5c9c3a59b2e56408c09bbe43f' 
  AND token = 'eqXA63UcSioTVkhB1/27pH79CdU+oVFKzrShsUzv52w=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}