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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a17235293ed2e53617c3d9e24eacf58404a9774c78b99686bbb56620fce7a780' 
  AND token = 'd5Ig641ArKCEVDIYWje/G/fEEkNNblwg8pt3Frcp0NI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}