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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7cd786f4af4c89846649ce008eecf7c9dfce6d0718e2e74d8a3e3de56871e2c4' 
  AND token = 'ZuvHlDpLCKTfkh+al6qoIaGAPVzEvvL0Mb9BGrN1/Hs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}