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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2905d11d2dda65a59740fcfa442149d972d11c4e0ccd2b73db68a7c3d7010f9' 
  AND token = '5wsTQzkqM6WAAN+9LHl/GFiCZRcJRlM5RRyA5YgTDPM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}