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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0fc46e2fd86377d2af3ba4790693a3097bc5ea4e52e0c01c79c6f57d7e226cc3' 
  AND token = 'Im+SLx4jZbRsM4kf6vfVVpSYmGm0yjBf7tOkaYpemJk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}