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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '538eea253f6a5ccf1aadd5131e6f63b7014e1cd7153d1230d662bfa0284c40d5' 
  AND token = 'TKjAV/aOsgWXCjvgWuYBhFG/d/kCjj/VrCQyM2t0iao=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}