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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25c976722f7a2c8171609c6933b7e2758e355f8e524984193f3c82ece7331c74' 
  AND token = 'nYJ17dbRYGfN/VHJHlIZsuBTKoNizNy2TWaoPWZxGt4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}