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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a232f678fe67e6d611a4ca2bd9551701c297da2cab09bafba182f1224b6d8815' 
  AND token = 'FrrBZbXA9DwcpCBy+2/jGSqtoSPSsdrpdsNj1+Zww9k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}