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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22d7110059ac548ecb66be58d43112c7c25af76f398d3aa5b76dc149bfc602b5' 
  AND token = 'rvRltyl0wea3yen04Pae6Bj2mJBshzBJsDOjwtp5hcM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}