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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '90a4fbdf052dd4ebdf78b75e123ead3dcb6f646bf1014c5605a2486cde70bbd7' 
  AND token = 'NNVTz12rOUFgz9BT5c4AMhoalzrMVgXJva3HaI6NKLs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}