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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a73bc54b5242b8078e1ab086aaeda1e6ee5ca90b1a95f557e03c7712e26e0195' 
  AND token = 'pDdvvNvutKRgRiHno4yNyxfn3WuRfFxtPDRAhJm+3co=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}