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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5741ed6e41f15eeb3843a9ffe5feaa4334ce73c592dc458f643916a4c9d29bc6' 
  AND token = 'S482KSRlaDFvyBRzmBpgJ7fdO7Lza2rMuZA7pKe/e0A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}