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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '539cd3941a9ccbbc0f7e18871395693365310633a2e2e491fb11dc61c41ea0f7' 
  AND token = '6Empqix4ClrKiwy8Bb2aLCXT8m6OJqGK06UeJ3Kf3ZE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}