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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4ca1f8d5bc9ff164d486191d88110035a193abb5aa5da901f50b048d5b52bfc8' 
  AND token = 'Pkg7rwOw2fyWwVBZOyA0BIQsY2YkbGyaJFcBnNN+JqQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}