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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0fe7b9229176becc290bd87f581941aa8590f5984301d4436ed4403a8060380' 
  AND token = 'bJ4kQT1iNQMsUZvInEnKbAXv/npAVFay1k6fqy23mEI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}