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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '42ef777743b1335a63fa1853fe4e0fb479ff5a9389e53769333f356b26012ea5' 
  AND token = 'Pa+64V+bP8ik1OXCCvsvN3oDyb4poISJOYYEPy6MdYw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}