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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3f24224f44a25c74af77a2453dec9cfbc491529e7e43355a9942091eca582da6' 
  AND token = '3wYrNmvPyng78uYr0Lkh7aTCcHJH7T5kmoldQLEJvYs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}