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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca4a28c5ff2aeade0d1172f1dcba8cde74adacb815baece8129555161f4d5859' 
  AND token = 'lcDBJPmrPEkJUxPZYuieNgeJscq51iAKwzGsYO5Q9WY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}