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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '09fdc467dd908358d6453cb1d989f05ba6903ef00b0d59dbb3ddc9431d9ab7c2' 
  AND token = 'SMk1VFRXc+i9Us4Vzxzf1rOTM1slRNGJ6p9/TTpmV3M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}