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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '464db6a99547f37336dc3befe8f737c3e33eec2305d96ff48a1e023342babe4d' 
  AND token = 'PzCQW1PsMhQXiMnrbQF6fDDP84QXrAhfuN03AAAmGOg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}