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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fa1dde9b96fdd581f184768242ae3deaca5cc2fddbcd3bf1df6a71b527f006ef' 
  AND token = 'b2E/AXSuPyfABNCZh8UqKsUKGLqVjqpCD78inYu0cCA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}