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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c440261bad28ff28826528fb9b6c8711a37a0138665db071c5c797630376c6d4' 
  AND token = '2JVWc4+NxmwuZAqaPJ00uPd0J826TCYstiF4nvdA1p0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}