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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8c161e680d7e82ae02a6279d330badf288e0634ae0bd4b6f6eef63dd0b1373ae' 
  AND token = 'HHlx6p2HFhuNtwWqPdMrMmUSn/1UMwj3K9yAnRDx6CE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}