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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f0a428a9a56aa727e38d3317b1db1a08495ad835b320a9fc86aa82bede779216' 
  AND token = 'AOTeqiZ7C+Xww7UfowEyF7wu9JP3ewQ8RNBCT6Yu5g0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}