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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b118e5314e9b78839ec5b9644c73be17da919d02b20a4f98308886475440fafa' 
  AND token = '4XNWK9FNdLAZmhcLhQW5eG4cVGJCnG4X17Pn9H6SCTk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}