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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5575edd0067e4915c3241c4ec6a6729eb9acc80db7488776a46ee6e9020007a8' 
  AND token = 'qRgt/GRDbC4kuGHwXszOfNC+y8284lgEB45RTWli8iI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}