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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12ad3218f0505e5bb793435202ab720bc95f8cf6b16f1152cbafc5459bd41014' 
  AND token = '/GR39zbE20lQ3qAg9rsPNinIJQx/VAZh+Eb+ChhhxmE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}