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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4d0465ba64d3cd4cd26bcb9d7caad7cad0a3c46c09005c1558311d0f9de8893' 
  AND token = '3FBFbCJ8nMSVrziJnAOrnbNyLuO7QivX1mD2sV3U3pU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}